10.国防科技创新特区项目,19-163-12-ZT-006-008-03、战场脑损伤****人机协同术式研究、2019.12- 2021.06、75万、结题、主持。 二、代表性论著:近期代表作,限10篇(部) 1.Zhu, Daren(#), Wang Yipeng(#), Wang Haiyan, Li Zhengchao, Li XiaoYin, Chen Xuyi, Su Bin(*), Wang Zhenguo(*). Assessment of eye tracking and facial expression as a model for depression identification: A preliminary study. General Hospital Psychiatry,2023, 09.004. 2.Liu Caiyun(#), Yu Haixin(#), Li Zhengchao, Chen Shulian, Li Xiaoyin, Chen Xuyi(*), Chen Bo(*). The future of artificial hibernation medicine: protection of nerves and organs after spinal cord injury. Neural Regen Res. 2024.19(1):22-28. 3.Xiao-Yin Li(#), Wu-Sheng Deng, Zi-Qi Wang, Zheng-Chao Li(#), Shun-Lian Chen(#), Zhen Song, Quan Zhang(#), Jin Liang(#), Xu-Yi Chen(#). Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous intracerebral hemorrhage: phase I clinical trial. Neural Regen Res. 2023.18(9):1999-2004 4.Xiao-Yin Liu(#), Yin-He Feng, Qing-Bo Feng, Jian-Yong Zhang, Lin Zhong, Peng Liu, Shan Wang, Yan-Ruo Huang, Xu-Yi Chen, Liang-Xue Zhou(#). Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury. Neural Regen Res. 2023.18(9):1990-1998 5.Xiaoyin Liu(#), Guijun Zhang(#), Pan Wei, Lin Zhong, Yaxing Chen(#), Jianyong Zhang, Xuyi Chen, Liangxue Zhou(#). Three-dimensional-printed collagen/chitosan/secretome derived from HUCMSCs scaffolds for efficient neural network reconstruction in canines with traumatic brain injury. Regenerative Biomaterials, 2022, 9, rbac043. 6.Ming Cheng(#), Hongxin Wang(#), Guang Yang(#), Yuanchi Cheng, Zhen Yang, Xuyi Chen, Yingfu Liu, Zhonglei Sun(*). Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway. Brain Research Bulletin. 2022: 65-76. 7.Wang Jianlong(#), Chen Xuyi(#), Hu Haijuan(#), Yao Mengting, Song Yanbiao, Yang Aimin, Xu Xiuhua, Zhang Ning, Gao Jianzhao(*), Liu Bin(*). PCAT-1 facilitates breast cancer progression via binding to RACK1 and enhancing oxygen-independent stability of HIF-1α. Mol Ther Nucleic Acids,2021,24:310-324. 8.Jiang Jipeng(#), Dai Chen(#), Liu Xiaoyin(#), Dai Lujia, Li Ruixin, Ma Ke, Xu Huiyou, Zhao Fei, Zhang Zhiwen, He Tao, Niu Xuegang(*), Chen Xuyi(*), Zhang Sai(*). Implantation of regenerative complexes in traumatic brain injury canine models enhances thereconstruction of neural networks and motor function recovery. Theranostics,2021,11(2), 768-788.
9.Li Xiao-Hong(#), Zhu Xiang(#), Liu Xiao-Yin, Xu Hai-Huan, Jiang Wei, Wang Jing-Jing, Chen Feng, Zhang Sai, Li Rui-Xin(*), Chen Xu-Yi(*), Tu Yue(*).The corticospinal tract structure of collagen/silk fibroin scaffold implants using 3D printing promotes functional recovery after complete spinal cord transection in rats. J Mater Sci Mater Med,2021, 32(4), 31. 10.Zhang Jian(#), Liu Xiaoyin(#), Ma Ke(#), Chen Miao, Xu Huiyou, Niu Xuegang, Gu Haoran, Wang Renjie, Chen Xuyi(*), Sun HongTao(*).Collagen/heparin scaffold combined with vascular endothelial growth factor promotes the repair of neurological function in rats with traumatic brain injury. Biomater Sci, 2021,9(3), 745-764. 三、授权专利: 1.王振国;陈旭义;苏彬;朱达仁;王晓瑜;李正超;李晓寅;陈淑莲, 一种基于支持向量机的抑郁识别方法和系统,2023.04,中国,2023100240540 2.王振国;苏彬;陈旭义;朱达仁;王晓瑜;李正超;陈淑莲;李晓寅,一种基于多模态数据的心理健康状态评估方法和系统,2023.04,中国,2023100237247 3.王振国;陈旭义;苏彬;朱达仁;李正超;王晓瑜;李晓寅;陈淑莲,一种基于多模态数据融合模型的抑郁识别方法和系统,2023.04,中国,2023100238659 4.王振国;孙圣凯;李正超;苏彬;李超;陈旭义;胡金朋;杜振华,一种丙氨酸氨基转移酶干化学试剂片及其制备方法,2023.03,中国,2023100237232
四、荣誉奖励: 2018,段 峰、陈旭义、张金、刘振强、崔冀宁、康培培、梁冰. 基于力导纳技术的全方位移动助力机器人产业化. 天津市科学技术进步奖. 二等奖 2020,陈旭义、段峰、何滔、李瑞欣、李正超、梁冰、张金、涂悦.神经支架联合仿生力学促进脊髓损伤再生修复关键技术研究与应用.天津市科学技术进步奖. 二等奖 2020,段峰、陈旭义、张金、杨怡康、薛佳宁、宫晓利.智能肌电假手关键技术.天津市科学技术进步奖. 二等奖
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